Mpox (formerly known as monkeypox) is a rare disease caused by the mpox virus, which is related to the viruses that cause smallpox and cowpox, but not to chickenpox. Despite the name, “monkeypox,” the exact source of the virus remains unknown.
The first human case was recorded in 1970, and since then, mpox has been reported sporadically in some countries. While generally milder than smallpox and rarely fatal, mpox typically causes a similar rash with milder symptoms.
On this page, you can explore how mpox spreads, who is at risk, what the symptoms are, how to prevent mpox, and information on mpox outbreaks.
The first human case was recorded in 1970, and since then, mpox has been reported sporadically in some countries.
Mpox can spread through direct contact with infected animals, close contact with an infected person (including intimate contact), and exposure to materials contaminated with the virus.
Anyone can contract mpox, although the illness is generally not life-threatening. However, certain groups may be at higher risk for severe illness, including:
The symptoms of mpox infection include:
The illness typically lasts 2–4 weeks. Sometimes, people get a rash first followed by other symptoms. Others only experience the rash.
There are available vaccines to prevent mpox. In consultation with their healthcare provider, people at higher risk for infection may consider vaccination. The mpox vaccines can also prevent infection if given immediately after exposure to an infected person.
Who is at higher risk for being infected by this virus?
The most recent large outbreak occurred in the summer of 2022, in which mpox spread across several countries that do not normally report mpox, including the United States. This outbreak mainly impacted people who reported having close, sustained physical contact with other people who have mpox. Due to a tremendous public health response in 2022 – 2023, low-level transmission of mpox is occurring in the U.S.
While many of those affected in this outbreak were men who have sex with men, anyone who has been in close contact with someone who has mpox can get the illness.
To learn more about the current situation of mpox, visit CDC’s Mpox in the United States and Around the World: Current Situation web page.
To ensure that your entire family is up to date on their vaccines, check out the following CDC recommended immunization schedules and talk to your healthcare provider.