What is Hib?

Haemophilus influenzae type b (HIB) is a very serious bacterial illness, especially for children under five years old. Even with good medical care as many as 1 in 20 kids who get sick with Hib meningitis will die from it, and up to 1 in 5 who survive will become deaf or have brain damage.

Hib disease primarily affects children under five, and adults 65 and older. Children under one year old have the highest rates of infection.

For the best protection against Hib, all children under 5 years old should receive the Hib vaccine.

On this page, you can explore how Hib spreads, who is at risk, what the symptoms are, whether Hib can lead to serious disease, and how to prevent Hib.

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Even with good medical care as many as 1 in 20 kids who get sick with Hib meningitis will die from it

How does this disease spread?

Hib spreads when an infected person coughs or sneezes. Usually the Hib bacteria primarily stay in a person’s nose and throat and often do not cause illness. However, if the bacteria spread to the lungs or bloodstream, they can lead to serious illness.

Since most mothers are immune to Hib through vaccination, they will pass antibodies to the infant before birth. These antibodies do not last long, so it’s important to get the child vaccinated according to the recommended immunization schedule . However, it’s possible that a newborn can be infected during birth if they inhale infected amniotic fluid or come into contact with genital tract secretions containing the bacteria.

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Who is at risk of Hib?

Several factors can increase the risk of serious disease:

1. Age : Children under 5, especially those younger than 1, and adults 65 and older are at higher risk. Infants have the highest infection rates.

2. Race and Ethnicity : Children of certain racial and ethnic groups, including African American or Black, Alaska Native, and American Indian children, experience higher rates of serious Hib disease.

3. Vaccination Status : Children who have not received all their Hib vaccines or are too young to be vaccinated are at greater risk for Hib disease.

4. Close Contact : People who live with or attend daycare with someone who has Hib disease may be at increased risk of infection.

5. Medical Conditions : Certain health conditions increase vulnerability, such as:

  • Sickle cell disease
  • Asplenia (lack of spleen)
  • HIV infection
  • Weakened immune system
  • Cancer treatments (chemotherapy, radiation, or bone marrow transplants)

Symptomless people can spread Hib through the air via coughs or sneezes, releasing respiratory droplets that others may breathe in.

What are the symptoms of Hib?

Hib causes a variety of symptoms depending on the part of the body that’s affected:

Mild symptoms:

  • Ear infection : Pain, redness, swollen ear drum, fever, sleepiness
  • Bronchitis : Cough, chest soreness, sleepiness, mild headache, mild body aches, sore throat

Symptoms of a serious infection:

  • Meningitis : Fever, headache, confusion, stiff neck, nausea, and sensitivity to bright light
  • Meningitis in babies : Poor feeding, vomiting, abnormal reflexes, moving slowly, and irritability
  • Pneumonia : Fever and chills/sweating, headache, cough, shortness of breath, muscle aches/pain, tiredness, and chest pain
  • Bloodstream infection : Fever and chills, extreme fatigue, pain in the stomach, diarrhea/nausea, anxiety, shortness of breath or difficulty breathing, and confusion
  • Epiglottitis : Difficulty breathing with a high-pitched sound when breathing in, fever, restlessness, irritability, sore throat, and drowsiness.
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Can Hib infection lead to serious disease?

 

Hib can cause both mild and serious diseases. While it is a common cause of ear infections in children and bronchitis (chest cold) in adults, it can also lead to more severe conditions. The most serious forms of Hib disease include:

  • meningitis (infection of the membranes surrounding the brain and spinal cord)
  • pneumonia (lung infection)
  • bacteremia (bloodstream infection)
  • cellulitis (skin infection)
  • infectious arthritis (joint swelling)
  • epiglottitis (swelling and inflammation of the throat)

Between 3% and 6% of Hib cases in children are fatal. Additionally, up to 20% of those who survive Hib-induced meningitis experience permanent hearing loss or other long-term neurological consequences.

Hib infections can result in sepsis, long-term complications, and death.

How can I prevent Hib?

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Babies and Children

For the best protection against Hib, all children under 5 years old should receive all recommended doses of the Hib vaccine (the number of doses depends on the vaccine brand). The schedule is:

  • 2 months
  • 4 months
  • 6 months (if needed, depending on the vaccine brand)
  • 12 through 15 months

The CDC also recommends that unvaccinated older children with certain medical conditions , as well as individuals who have received a bone marrow transplant, get the Hib vaccine. Be sure to talk to your healthcare provider about the best vaccination plan for your child’s specific needs.

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Adults

The CDC recommends Hib vaccine for unvaccinated adults with certain risk factors . Talk to your healthcare provider about what is best for your specific situation.